Delirium Clinical Pathway — CICU, PICU, and PCU

Trial of Pharmacological Therapy: Monitoring Parameters

Monitoring Parameters for Recommended Approach

General Monitoring: HR, BP, Temperature, Extrapyramidal symptoms (EPS), Neuroleptic Malignant Syndrome (NMS)
See AACAP Practice Parameters for Atypical Antipsychotic Medications for more guidance on EPS and NMS.

Laboratory Monitoring:

Parameter	Baseline	After Initiation and Subsequent Dose Increase(s)	Maintenance (if continued)
EKG	X	48 hours	Monthly (enteral agents) Weekly (IV haloperidol)
BMP	X
Magnesium	X
CPK	X	Weekly x 2	Monthly
CBC with diff	X
LFTs	X
Triglycerides	X	Monthly	Monthly

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The clinical pathways are based upon publicly available medical evidence and/or a consensus of medical practitioners at The Children’s Hospital of Philadelphia (“CHOP”) and are current at the time of publication. These clinical pathways are intended to be a guide for practitioners and may need to be adapted for each specific patient based on the practitioner’s professional judgment, consideration of any unique circumstances, the needs of each patient and their family, and/or the availability of various resources at the health care institution where the patient is located.

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